Environmental or self-antigens and homotypic interactions induce BCR and Toll-like receptor (TLR) signaling, amplifying the response of CLL cells to other alerts from your microenvironment and escalating the activation of anti-apoptotic and proliferation pathways.31,32 Genomic research have identified recurrent mutations in genes regulating tumor cell-microenvironment interactions, wh... https://jenningsv998lct7.dreamyblogs.com/profile