Fewer than three% of the administered dose is excreted unchanged in urine. The relationship between dose and total valproate focus is nonlinear; focus will not maximize proportionally with the dose, but relatively, improves to some lesser extent because of saturable plasma protein binding. The kinetics of unbound drug are linear. https://dapattoto80245.myparisblog.com/33957994/5-simple-statements-about-dapatoto-explained