There's a release of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors inside the dorsal horn to minimize afferent agony transmission and deliver analgesia. Hence, medications like clonidine that goal alpha-two receptors can influence the transmission of soreness. Clonidine is distributed in breast milk; warning is https://bookmark-media.com/story19913278/everything-about-onolidine